Practical, research-based guide to testosterone optimization — covering the HPA axis, SHBG, free testosterone, and the lifestyle and clinical factors that influence the androgen system. Relevant to AR, LEPR, and testosterone pathway research.
Vergel synthesizes the endocrinology of the male HPG axis — free vs. total testosterone, SHBG, estradiol, DHT, aromatase — with practical clinical strategies: lifestyle levers (sleep, resistance training, body composition), testing schedules, TRT protocols, and side-effect management.
One of the most-referenced patient-facing books on testosterone optimization — Vergel is a long-time patient advocate whose material has been vetted by leading urologists in the field.
These peer-reviewed studies connect to the core ideas in this book. Each result has been scored for reliability.
Covers the full endocrine system with a focus on evidence-based lifestyle approaches to hormonal balance — testosterone, estrogen, cortisol, thyroid, and insulin. Relevant to ESR1, TSHR, LEPR, and CYP17A1 research.
The most practical guide to thyroid function beyond TSH — covering the genetics of thyroid hormone conversion, autoimmune thyroid conditions, and why standard thyroid tests often miss the full picture. Relevant to TSHR and THRA research.
Covers adaptogen research including ashwagandha, rhodiola, and phosphatidylserine in the context of HPA axis support. More practical and supplement-focused than the physiology books — relevant to cortisol management strategies for FKBP5 CT carriers.